"The bucket is in a different region"

The bucket exists, but in a different region from the one in Offloft's settings. Your provider returned AuthorizationHeaderMalformed, PermanentRedirect or IllegalLocationConstraintException. Open Settings → Connection, choose the region the bucket was created in, then test again. A bucket's region can't be changed.

To find it, open the bucket in your provider's dashboard. Its region is shown with the bucket. Region names look like eu-west-1 or nyc3, depending on the provider.